Introduction

Welcome to www.crusadebleedingscore.org. The purpose of this website is to help clinicians estimate a patient's baseline risk of in-hospital major bleeding during non-ST-segment elevation myocardial infarction (NSTEMI).

The CRUSADE Bleeding Score was developed using data from over 89,000 "real-world" patients enrolled in the CRUSADE Quality Improvement Initiative that presented with NSTEMI. We developed (n=71,277) and validated (n=17,857) a logistic regression model to identify eight independent predictors of in-hospital major bleeding. The CRUSADE Bleeding Score was created by assigning a weighted integer to each predictor based on its coefficient in the regression model. A patient's CRUSADE Bleeding Score equals the sum of the weighted scores for the independent predictors (range 1-100 points).

The CRUSADE Bleeding Score considers baseline patient characteristics (female sex, history of diabetes, peripheral vascular disease), admission clinical variables (heart rate, systolic blood pressure, signs of CHF), and admission laboratory values (hematocrit, calculated creatinine clearance) to estimate the patient's likelihood of having an in-hospital major bleed event. While treatments increase the likelihood of bleeding, they were not included in the model as they are post-admission variables. However, the CRUSADE Bleeding Score was tested across post-admission treatment subgroups (e.g. invasive care, use of anticoagulants), and found to perform consistently across the subgroups. To use the Crusade Bleeding Score risk calculator, please input the appropriate range of each predictor from the drop-down bar. The CRUSADE Bleeding Score and estimated risk of major bleeding will appear below the calculator.